(*1*)
People who’ve had type 1 diabetes for greater than 50 years with out kidney problems should still be at substantial threat for heart disease, regardless of glorious control of blood strain, ldl cholesterol and blood sugar ranges, in accordance with a examine offered Saturday at ENDO 2024, the Endocrine Society’s annual assembly in Boston, Mass.
Heart disease is a serious trigger of loss of life in folks with type 1 diabetes, particularly in those that develop kidney problems from diabetes.
As folks with type 1 diabetes reside longer on account of improved medical care, a considerable proportion of these sufferers survive with out kidney problems, however are nonetheless at excessive threat for heart disease,” mentioned
Marc Gregory Yu, M.D., lead researcher of the Joslin Diabetes Center and Harvard Medical School in Boston, Mass.
Yu and colleagues examined information from a affected person group often known as the “Medalists,” consisting of greater than 1,000 people from throughout the United States who’ve had type 1 diabetes for over 50 years. The “Medalists” are noteworthy as a result of solely 13% have kidney problems from diabetes, and most even have glorious control of blood strain, ldl cholesterol, and blood sugar levels-;all conventional threat components for heart disease. Despite this, round 40% of them nonetheless report having heart disease.
From the general examine group of greater than 1,000 folks, 153 underwent CT scans to detect calcium deposits within the heart’s blood vessels, and 111 underwent MRI imaging to judge the heart’s total construction and pumping capability. The “Medalists” had greater calcium deposits within the heart’s blood vessels, though with comparable heart construction and performance, in comparison with different people of the same age with type 1 or type 2 diabetes. Higher blood sugar ranges among the many Medalists have been additionally noticed to be intently linked to heart disease. “This highlights the continued significance of blood sugar control in type 1 diabetes regardless of advancing age,” Yu mentioned.
“We likewise noticed that threat components for heart disease might differ among the many ‘Medalists’ after they have been grouped in accordance with those that have and do not have kidney problems from diabetes,” Yu mentioned. “These threat components may be totally different for type 1 diabetes generally, as in comparison with type 2 diabetes. The findings might assist information the event of new drugs particularly focused for heart disease in type 1 diabetes.”